Four-directional synthesis of adamantane derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis and antimicrobial activity of new adamantane derivatives III.
Some novel ester imides synthesised from trimellitic acid anhydride and 1-adamantanol or 2-adamantanol, were tested as antimicrobial compounds. Unfortunately, these agents showed a modest antibacterial activity (MIC > 6 microg/ml). However, a comparison of these N-substituted adamantylester imides with the series published previously, indicated that the incorporation of L-alanine and L-phenylal...
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Adamantyl-based compounds are commercially important in the treatments for neurological conditions and type-2 diabetes, aside from their anti-viral abilities. Their values in drug design are chronicled as multi-dimensional. In the present study, a series of 2-(adamantan-1-yl)-2-oxoethyl benzoates, 2(a-q), and 2-(adamantan-1-yl)-2-oxoethyl 2-pyridinecarboxylate, 2r, were synthesized by reacting ...
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Marcy, R. et al.; J. Pharmacol. 13 (1), pp. 163-164 (1982). Miura, Y. et al.; Japan. J. Pharmacol. 39, pp. 443-451 (1986). Mi1tner, F. 0.; Arzneimittelforschung. 32 (10), pp. 1268-1270 (1982). Mi1tner, F. 0.; Arzneimittelforschung. 32 (10), pp. 1271-1273 (1982). Hamoen, A. M.; British Medical Journal. 3, (5874), pp. 272-273 (1973). Kinomota, H. et al.; No Skinkei Geka, 12 (1), pp. 37-45 (1984)....
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A new series of adamantane-isothiourea hybrid derivatives, namely 4-arylmethyl (Z)-N'-(adamantan-1-yl)-morpholine-4-carbothioimidates 7a-e and 4-arylmethyl (Z)-N'-(adamantan-1-yl)-4-phenylpiperazine-1-carbothioimidates 8a-e were prepared via the reaction of N-(adamantan-1-yl)morpholine-4-carbothioamide 5 and N-(adamantan-1-yl)-4-phenylpiperazine-1-carbothioamide 6 with benzyl or substituted ben...
متن کاملDifferentiability via Directional Derivatives
Let F be a continuous function from an open subset D of a separable Banach space X into a Banach space Y. We show that if there is a dense G8 subset A of D and a Gs subset H of X whose closure has nonempty interior, such that for each a E A and each x E H the directional derivative DxF(a) of F at a in the direction x exists, then F is Giteaux differentiable on a dense G8 subset of D. If X is re...
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2020
ISSN: 1551-7012
DOI: 10.24820/ark.5550190.p011.237